Oct 2026
Vascular-specific FAM43B inhibits the Wnt pathway by regulating β-catenin ubiquitination and alleviates the progression of atherosclerosis.
AIMS Current therapies cannot completely halt atherosclerotic plaque progression and plaque destabilization, making it critical to discover core genes maintaining vascular homeostasis. Preliminary transcriptomic data revealed that FAM43B is enriched in vascular endothelial and smooth muscle cells, yet its cardiovascula...
Yun-Kai Wang, Xiao-Yang Li, Ye-Shun Wu et al.
· Life Science · 0 citations