Spatial and single-cell dissection of medulloblastoma identifies developmental hierarchies and a prognostic PPIA-BSG tumor-immune axis
Medulloblastoma (MB) in children is highly heterogeneous, leading to its classification into molecular subgroups and resulting in significant differences in clinical outcomes even within the same risk group. This heterogeneity severely hampers the clinical management of MB. Therefore, it is essential to characterize MB...