Author

Jing Zhuang

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Review Open access Oct 2026

Targeting the gut–brain axis: novel strategies for disease intervention from mechanisms to clinical practice

The gut–brain axis is a bidirectional communication network linking the gastrointestinal tract and the central nervous system (CNS), in which the gut microbiota and its metabolites have emerged as important modulators. Alterations in the gut microbiota have been reported in a range of neurological, psychiatric, and met...

Le-Le Fan, Yu-Ying Guo, Jin Liu et al. · Frontiers in Microbiology · 0 citations

Open access Jul 2026

Single-cell RNA-seq and spatial transcriptomics characterize CD8+ exhausted T cells in pancreatic ductal adenocarcinoma

Low SPP1 and PLAUR expression correlated with poor prognosis in TCGA-PAAD and two key LR pairs mediated crosstalk between cancer cells and CD8+ Tex cells, confirmed by immunofluorescence, spatial mapping, and protein docking.

Jing Mao, Chenxin Yan, Ying Mei et al. · iScience · 0 citations