Aug 2026
Loss of PHD3 rescues mice from Neuroinflammation and cognitive disorders induced by lipopolysaccharide or surgical trauma.
OBJECTIVE Neuroinflammation is recognized as a contributing factor to cognitive disorders. Previous studies have demonstrated PHD3 drives microglia-mediated neuroinflammation. Present study aims to further clarify the role of PHD3 in both lipopolysaccharide (LPS)- and anesthesia/surgery (AS)-induced neuroinflammation a...
Ji Che, Yixu Deng, Xiang Zhang et al.
· Experimental Neurology · 0 citations