Open access
Aug 2026
CRISPR/Cas9-mediated generation of a homozygous MT4 knockout mouse embryonic stem cell line.
The CRISPR/Cas9 system is utilized to generate a homozygous Mt4 knockout (Mt4-/-) mouse embryonic stem cell (mESC) line that maintains normal morphology, pluripotency, and the ability to differentiate into all three germ layers.
Huan-Xin Zhou, Yine Li, Meiyan Jia et al.
· Stem Cell Research · 0 citations