Sep 2026
Next-Generation Solid Dispersion of Andrographolide Attenuated Inflammation and Oxidative Stress in an Activated RAW264.7 Macrophage-Based In Vitro Model Relevant to Ulcerative Colitis
Ulcerative colitis (UC) is fundamentally mediated by macrophage-driven immune dysregulation that amplifies mucosal inflammation. Andrographolide (AGD) has potent anti-inflammatory and antioxidant properties; however, AGD shows poor water solubility and bioavailability. To surmount these challenges, next-generation soli...
Pawan Devangan, Dinesh Kumar Chandanpalli, Atul Mourya et al.
· AAPS PharmSciTech · 0 citations