Open access
Jul 2026
HOF‐Stabilized Apple EV Nanocargo in an NIR‐Responsive Hydrogel Enables On‐Demand Therapeutic Modulation for Transdermal Deep‐Joint Osteoarthritis Therapy
The NIR‐activated platform is associated with reduced joint inflammation and edema, attenuated oxidative stress, improved macrophage polarization toward an anti‐inflammatory phenotype, enhanced gait‐related joint function, and preservation of cartilage structure in an OA rat model.
Yu-Wen Tseng, Pei-Wei Weng, Hsien-Tsung Lu et al.
· Advanced Healthcare Material... · 0 citations