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Author

Joan Wither

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3 papers indexed here

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Open access Oct 2026

Investigating the association between interferons and flares of systemic lupus erythematosus at a single cell level

Elevated levels of interferons (IFN) are a hallmark of Systemic Lupus Erythematosus (SLE) and are linked to disease flares, but the precise mechanisms underlying this remain unclear. We examined the association between IFN-stimulated proteins (ISPs) and immune changes in flaring and quiescent SLE patients at single...

Zoha Faheem, Giselle M. Boukhaled, Carol Nassar et al. · 0 citations
Aug 2026

Alterations in Innate Immune Cells During the Progression of Systemic Autoimmune Rheumatic Diseases

To evaluate functional alterations in innate immune populations during SARD development, CITE-Seq was conducted on innate immune cells from 24 patients including healthy controls, non-progressor (NP), high or low, progressors (P), or SARD patients to validate differences in CITE-Seq genes of interest.

C. Ucciferri, Carol Nassar, S. Johnson et al. · 0 citations
Aug 2026

Characterizing Memory T Cells Associated with Systemic Lupus Erythematosus Pathogenesis

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease associated with a severe morbidity and mortality. Around 70% of SLE patients follow a relapse-remitting pattern of disease characterized by flares of disease activity, followed by prolonged periods of disease quiescence. Memory CD4+ T cell subsets h...

C. Nassar, Rene Quevedo, M. Ciudad et al. · 0 citations

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