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João Pedro Araujo da Costa Aires

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2025

The broad spectrum of immune dysregulation: clinical cases

INTRODUCTION: Inborn errors of immunity are classified according to the many possible genetic defects, and 25% manifest as immune dysregulation. CTLA-4 (cytotoxic T-lymphocyte antigen 4) haploinsufficiency has been associated with variable clinical presentations, ranging from asymptomatic carriers (30%) to patients wit...

João Pedro Araujo da Costa Aires, Paula Christina Cavallini de Melo Maricondi, A. Grumach et al. · 0 citations

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