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#machine learning Preprint Sep 2026

From DNA Design to DNA Slimming: Auditable Agentic Discovery of a Deletion-Only Designer

Compact regulatory DNA can free up space in vector payloads, reduce synthesis and assay burden, and expose which sequence features drive predicted activity. Yet most model-based nucleic-acid designers optimize fixed-length sequences through substitutions; they do not ask which bases of an existing functional element ca...

Joel Shor · 0 citations

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