Johan Geiser

Decoding how RNase E membrane targeting controls RNA degradosome activity in Pseudomonas aeruginosa

Summary In many Proteobacterial species, transcription and RNA degradation are physically separated through segregation of the main ribonucleolytic machinery—the RNA degradosome—into RNase E-driven membrane-anchored assemblies that form discrete foci. Despite widespread conservation of the amphipathic membrane-targetin...