Open access
Sep 2026
SpectrSeqTools: LC-MS/MS-Based De Novo Sequencing of Small Ribonucleic Acids with Post-Transcriptional Modifications
Post-transcriptional RNA modifications are key regulators of fundamental cellular processes. Yet, their precise biological functions remain largely unresolved. A major challenge is their reliable detection. While sequencing-based approaches are limited to a small subset of RNA modifications, mass spectrometry has the...
Laura C. Kühle, M. Harsh, Shanice Jessica Hermon et al.
· Analytical Chemistry · 0 citations