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Johannes Riechel

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Open access Aug 2026

Antibody-mediated inhibition of ADAMTS-7 reduces experimental atherosclerosis

Objective One of the strongest genetic associations with coronary artery disease (CAD) risk maps to the metalloproteinase ‘a disintegrin and metalloproteinase with thrombospondin motifs 7’ (ADAMTS-7) locus. The protein was shown to promote plaque formation and instability. We aimed to generate and evaluate an antibody-...

M. A. Sharifi, Johannes Riechel, Michael Winkler et al. · 0 citations

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