Beauveria bassiana is a filamentous fungus that has considerable potential to combat insect pests. Therefore, an easy to use genetic transformation tool helps to investigate which fungal genes play a role in virulence and host specificity. However, B. bassiana is often very resistant to antibiotics used as selective ag...
M. V. van Belkum, Anjalee Wijewardane McKee, John C. Vederas· Journal of Microbiological M...· 0 citations
A covalent pan-coronaviral inhibitor that targets 19 Mpros across the α, β, γ, and δ genera, encompassing bat, human, and other animal coronaviruses, AVI8122 exhibits low nanomolar potency and favorable pharmacokinetics in mice and is positioned as an early lead compound and a tractable structural starting point for th...
Pu Chen, Ulrike Strunk, E. Arutyunova et al.· Journal of Medicinal Chemist...· 0 citations
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