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John F. Dawson

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Open access Aug 2026

Early pre-symptomatic and sex-specific cardiac remodeling precedes heart failure in zebrafish with human actin mutation.

It is demonstrated that the Acta1b p.T126I mutation drives progressive, sex-specific DCM in zebrafish, highlighting biological sex as a critical modifier of sarcomeric cardiomyopathy progression and targeted therapy development.

K. Prill, John F. Dawson · 0 citations

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