Clinical Translation of Mesenchymal Stem Cells to Medicinal Signaling Cells: Origins, Clinical Applications, and the Future of Regenerative Medicine-2026 Arnold I. Caplan Award for Distinguished Research in Orthobiologics.
Orthobiologics are used widely in modern orthopaedic and sports medicine practice, yet the biologic rationale for cell-based therapies is often oversimplified. Mesenchymal stem cells (MSCs) were initially understood as multipotent progenitors capable of regenerating mesenchymal tissues through engraftment and different...