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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Jong Oh Kim

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Aug 2026

Rational Design of Pyrrole-Based Ionizable Lipids for mRNA Delivery.

Ionizable lipids are key components of lipid nanoparticles for mRNA delivery. Inspired by the DLin-KC2-DMA ionizable lipid, we developed a series of pyrrole-based ionizable lipids to evaluate the feasibility of incorporating a rigid heterocyclic scaffold into ionizable lipid design. Systematic variation of headgroup ar...

Beomsu Kim, Thi Oanh Oanh Nguyen, R. H. Patil et al. · 0 citations

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