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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Jordan Breffle

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Open access Aug 2026

Target-biology and interactome-derived signatures predict target-level associations with safety-related drug attrition

A target-centric framework that integrates network medicine principles with target biology features to predict operational target-level labels associated with safety-related drug attrition is proposed and suggests that target biology and interactome context contain signal associated with safety-related clinical attriti...

Jordan Breffle, Alex Jones, S. Ghiassian · 0 citations

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