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Jorge A. Colón-Rosado

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Open access Aug 2026

A Draft Map of E. coli Proteoforms

Top-down proteomics (TDP) enables direct characterization of intact proteoforms, providing protein-level insights into molecular diversity arising from post-translational modifications and sequence variations. Despite this advantage, proteome coverage in TDP remains limited relative to bottom-up proteomics (BUP). To ex...

Jorge A. Colón-Rosado, Fei Fang, Liang-Liang Sun · 0 citations

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