Open access
Jul 2026
Extracellular vesicles from cytokine-treated human pancreatic ductal cells enhance HLA class I expression in beta cells
Introduction/objective Type 1 diabetes (T1D) is an autoimmune disease characterized by the loss of insulin-producing beta cells and has no cure. The role of cell-cell interactions in T1D disease progression remains poorly understood. Beta cells develop adjacent to ductal cells and both cell types undergo changes during...
Neslihan Erdem, H. Zook, Janine C. Quijano et al.
· Frontiers in Immunology · 0 citations