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José de Jesús Pérez-Becerra

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Open access Sep 2026

Contribution of MTHFR C677T and A1298C Variants to Retinoblastoma Risk in Mexican Children

Background: Retinoblastoma (RB) is the most common malignant intraocular tumor in childhood. Although germline and somatic alterations in RB1 contribute to RB development, additional genetic factors may influence susceptibility. Methylenetetrahydrofolate reductase (MTHFR) participates in folate metabolism and DNA synth...

José de Jesús Pérez-Becerra, Juan Antonio Ramírez-Corona, David Fernández-Sánchez et al. · 0 citations

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