Oleanolic acid (OA) is a privileged pentacyclic triterpenoid scaffold displaying moderate antiproliferative properties, whereas selenocyanates are recognized organoselenium pharmacophores with promising anticancer potential. To explore possible synergistic effects, we designed and synthesized an unprecedented library o...
Rosa I. Martínez-Lara, Aday González-Bakker, Adam N. Khan et al.· Bioorganic chemistry (Print)· 0 citations
Two complementary series of novel tryptophan‐derived dipeptides (Trp‐X and X‐Trp) were designed and synthesized to systematically evaluate how backbone sequence inversion alters chemical accessibility and in vitro antineoplastic profiles against a human solid tumor cell line panel (A549, HeLa, MIA PaCa‐2, SW1573, T‐47D...
J. B. Díaz, Adam N. Khan, Aday González-Bakker et al.· Journal of Peptide Science· 0 citations
Randia monantha, commonly known as crucetillo, is a medicinal plant traditionally used in Mexico to treat conditions such as diabetes, venomous animal bites, and cancer; however, its effects on cancer cell viability remain underexplored. In this study, hexane, ethyl acetate, and methanolic extracts from the leaves and...
Eugenia Elisa Delgado-Tiburcio, Ivonne Pérez-Bautista, R. M. Soto-Hernández et al.· Molecules· 1 citation
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