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Author

Josef Shin

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Review Aug 2026

Immune-mediated excitotoxicity in brain disorders.

The concept of excitotoxicity is extended beyond glutamate receptor overactivation to include innate and adaptive immune pathways, introducing the framework of immune-mediated excitotoxicity and defining three hallmarks - feedback, stressor and chronicity - as organizing principles of this paradigm.

Josef Shin, C. Vogelaar, Stefan Bittner et al. · 0 citations