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Author

Joseph M. Cunningham

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Open access Aug 2026

Spatial analysis reveals cellular microenvironments and mechanisms of inflammation and injury in acute interstitial nephritis

Acute interstitial nephritis (AIN) is present in 15-20% of all acute kidney injury cases but lacks proven effective therapies beyond corticosteroids. Using high-resolution imaging mass cytometry and single-cell spatial transcriptomics to analyze human kidney biopsies with AIN, acute tubular injury (ATI), and reference...

Megan L. Baker, Vijayakumar R. Kakade, Tifanny Budiman et al. · 0 citations

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