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Joshua H. Siegle

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Open access Sep 2026

3D-MAESTRO: A scalable, modular, portable pipeline for automated processing of large-scale volumetric brain microscopy data

Light microscopy is routinely used to explore the cellular and molecular structure of tissues, but the scale and complexity of data remains a bottleneck for discovery. We introduce 3D-MAESTRO (3D-Microscopy Automation and Execution with Scalable Tools, Rendering, and Orchestration): an automated image processing workfl...

Camilo Laiton, Nicholas A. Lusk, Yoni Browning et al. · 0 citations
Open access Jul 2026

Map of spiking activity underlying change detection in the mouse visual system.

A database of spiking activity across the mouse visual system-including the cortex, thalamus, and midbrain-while mice perform an image change detection task is presented, providing a valuable substrate for understanding sensorimotor computations in neural networks.

Corbett Bennett, Samuel D. Gale, Greggory Heller et al. · 0 citations

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