Author

Joshua Levitz

2 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Sep 2026

Structural basis of active state coupling of metabotropic glutamate receptor 8 to beta-arrestins

Metabotropic glutamate receptors (mGluRs) are prototypical, dimeric family C G protein-coupled receptors (GPCR) that perform crucial modulatory roles throughout the nervous system. While mGluR activation and signaling through G proteins has been studied extensively, how these receptors interact with and are desensitize...

Dagan C. Marx, Kevin Huynh, Alberto J. Gonzalez-Hernandez et al. · Nature Communications · 1 citation

Open access Sep 2026

Configurational diversity of metabotropic glutamate receptor complexes with beta-arrestins

Beta-arrestins (β-arrs) are cytosolic proteins which mediate G protein-coupled receptor (GPCR) desensitization, endocytosis, and signaling. Despite the widespread physiological roles of β-arr coupling, the molecular basis of GPCR/β-arr interaction has been studied primarily in monomeric family A GPCRs. Here we develop...

Dagan C. Marx, Alberto J. Gonzalez-Hernandez, Joon Lee et al. · Nature Communications · 1 citation