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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Ju Chen

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2 papers indexed here

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Open access Oct 2026

Distinct genetic perturbations at the endogenous Atf4 locus uncouple polyadenylation loss from transcriptional readthrough

Transcription termination by RNA polymerase II (RNAPII) is coupled to co-transcriptional cleavage and polyadenylation directed by the canonical AAUAAA polyadenylation signal (PAS). However, the in vivo requirement of the canonical PAS for termination fidelity remains unclear. Here, we dissect PAS-dependent terminat...

Zeng-Ming Zhang, Tong-Bin Wu, Ze-Yu Chen et al. · 0 citations
Open access Oct 2026

Cardiomyocyte Perm1 sustains cardiac bioenergetic reserve and exercise capacity

Objective The PGC-1/ERR axis controls both steady-state mitochondrial respiration and the capacity to expand ATP production on demand, but whether this reserve function requires dedicated downstream effectors, and whether its loss is detectable at rest, remain unclear. We tested whether Perm1, a striated muscle-specifi...

Shizuko Tachibana, Tina Le, Simon Schenk et al. · 0 citations

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