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Author

Ju-Ling Wang

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Open access Sep 2026

Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1–JUN/FOS Axis

It is demonstrated that IDH3A is significantly overexpressed in melanoma, primarily due to DNA copy number amplification, and a noncanonical role of IDH3A is uncovered as a nuclear regulator of transcription via YBX1, offering novel insight into metabolic enzyme reprogramming in melanoma.

Juan Ran, Yan-Chun Fang, Sheng-Ming Ruan et al. · 0 citations

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