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J. Lu

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Open access Aug 2026

Bridging structure and function: triple network remodeling driven by white matter hyperintensities in vascular cognitive impairment.

Cerebral small vessel disease-induced vascular cognitive impairment (VCI) is a major contributor to the pathogenesis of dementia. Accumulating evidence suggests that VCI disrupts large-scale brain networks, but how it selectively impairs inter-network connectivity and contributes to specific cognitive deficits remains...

Jing Jin, Jie Ma, Jia-Jia Wu et al. · 0 citations
Open access Aug 2026

Early functional disconnection of the basal forebrain-hippocampal system predicts memory impairment in amnestic mild cognitive impairment.

Directional connectivity alterations within the BF-hippocampal-cortical axis were observed in patients with aMCI in the absence of detectable macroscopic atrophy, highlighting the potential contribution of BF-related network dysfunction to early disease processes.

Juan-Juan Lu, Zhi-Jie Xu, Jie Ma et al. · 0 citations

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