Mannose Glycation of Tumor-Associated Antigens via Intratumoral Maillard Reaction Mediated by a Photothermal Nano-Catalyst for Enhanced Antigen-Presenting Cell Targeting.
Immunogenic cell death (ICD) represents a classical pathway for generating personalized anticancer vaccines in situ. However, the poor immunogenicity of released tumor-associated protein antigens (TAAs) remains a major limitation to their therapeutic efficacy. Herein, we developed mannose-loaded hollow polydopamine nan...