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Open access Sep 2026

TRIM28 Promotes Keratinocyte Proliferation and Invasion by Activating NLRP3/SGT1 Axis‐Mediated Macrophage Pro‐Inflammatory Polarization in an In Vitro Macrophage–Keratinocyte Co‐Culture Model

Macrophage–keratinocyte crosstalk is an important component of cutaneous inflammatory responses. Psoriasis is a chronic inflammatory skin disease characterized by dysregulated keratinocyte proliferation and immune dysfunction. While macrophage pro‐inflammatory activation is known to exacerbate psoriatic inflammation, t...

Zhe Gao, Xin Zhang, Juan Wang et al. · 0 citations

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