Open access
Jul 2026
Quercetin induces ferroptosis in ovarian cancer by suppressing the NRF2/HO‑1/GPX4 axis and increasing the efficacy of cisplatin.
It is revealed that Quer induces ferroptosis in OC cells at least partially through NRF2/HO-1/GPX4 antioxidant axis suppression and cisplatin effectiveness enhancement and these findings support further evaluation of Quer as a ferroptosis-priming adjunct to platinum-based OC therapy.
Hui Li, Zhaoxuan Liu, Hai-Long Shi et al.
· Biochemical Pharmacology · 0 citations