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Open access Aug 2026

Polygenic risk scores, adiposity, and disease transition in type 2 diabetes and colorectal cancer comorbidity: a population-based Chinese cohort study

The co-occurrence of type 2 diabetes (T2D) and colorectal cancer (CRC) represents an increasing public health concern, contributing to greater clinical complexity and poorer outcomes. This study aimed to evaluate whether polygenic risk scores (PRS) for T2D and CRC are associated with the risk of T2D-CRC comorbidity and...

Bing Liu, Jue Xu, Cai-Xiao Jiang et al. · 0 citations

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