Engineering the interface: pH-dependent self-assembly of lysine-tyrosine synthetic copolypeptides for anti-biofilm implant coatings.
While pK30Y10 coatings effectively disrupted both pathogens, the optimal assembly state for biomass reduction differed between Staphylococcus aureus and Pseudomonas aeruginosa, suggesting that the biological efficacy is not merely a product of chemical composition, but a direct consequence of how the block architecture...