Jul 2026
Abstract B093: Combinatorial CRISPR screening reveals synthetic lethal and suppressor interactions in RTK signaling and glycosylation networks
The N-glycosylation module is demonstrated as a recurrent hub of context-dependent genetic interactions and combinatorial CRISPR screening as a scalable approach for identifying therapeutic targets and resistance mechanisms in oncogene-driven cancers.
Subin Kim, Chenchu Lin, Sabriyeh Alibai et al.
· Clinical Cancer Research · 0 citations