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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Julia Freitag

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Open access Aug 2026

Sex-specific effects of resveratrol and metformin on mitochondrial function and inflammatory activation in a TNF-α-driven human iPSC-derived endothelial dysfunction model

Findings highlight cellular sex as a critical determinant of endothelial immunometabolic responses to inflammatory stress and suggest that resveratrol- and metformin-based strategies for vascular protection should be evaluated in a sex-aware manner.

Julia Temp, E. Strässler, Julia Freitag et al. · 1 citation

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