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Author

Julia Sellin

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Open access Jul 2026

Plasma cardiac troponin T complements neurofilament light chain by reflecting disease phase and phenotypic variation in amyotrophic lateral sclerosis

While NfL reflects disease aggressiveness, hs-cTnT aligns with disease phase and clinical phenotype, supporting its use as a complementary biomarker for ALS characterisation and monitoring.

Julia Sellin, Linn Öijerstedt, Janina von der Gablentz et al. · 0 citations
Open access Jul 2026

Troponin T and Neurofilament Light Chain Levels as Complementary Biomarkers of Disease Accumulation and Aggressiveness in Amyotrophic Lateral Sclerosis

The results suggest that TnT and sNfL capture different dimensions of disease status within the D50 framework, and further longitudinal studies are needed to determine whether combining these biomarkers improves disease stratification or prognostic assessment in clinical practice and therapeutic trials.

Julia Sellin, Sofia Waldorf, Janina von der Gablentz et al. · 0 citations

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