Author

Julian Reading

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Open access Sep 2026

Deconvolution of the mechanisms of T cell drug response in multiple myeloma induction therapy

Lenalidomide (Revlimid™), bortezomib (Velcade™), and dexamethasone, are used alone or in combination (RVd therapy) as first-line therapies for hematologic malignancies including the plasma cell dyscrasia, Multiple Myeloma (MM). The effects of RVd treatment on tumor cells have been documented, but little is known about...

Lucas T. Graybuck, L. Okada, Wei-Ling Chang et al. · bioRxiv · 0 citations

Open access Aug 2026

High-Dimensional Spectral Flow Cytometry Panel for Immunophenotypic Characterization of Fixed Whole Blood Samples.

Peripheral blood mononuclear cells (PBMCs) are commonly used for immune profiling in clinical research, but their isolation and cryopreservation present logistical challenges, particularly in settings with limited access to research facilities. To address this, we implemented a whole blood fixation protocol to preserve...

V. Parthasarathy, A. Heubeck, Tyanna J. Stuckey et al. · Cytometry Part A · 0 citations