Open access
Sep 2026
SALL1 and neural microenvironmental context specify identity of stem cell derived human microglia-like cells
Microglia, the immune cells of the brain parenchyma, play a pivotal role in neurodevelopment and neuroprotection. Human stem cell-derived microglia-like cells (MGL) offer a valuable, human-relevant system to study microglia in vitro. However, their cell states and intercellular interactions within complex 3-dimensional...
Marina T. Nikolova, Kiara Freitag, Ryoko Okamoto et al.
· bioRxiv · 0 citations