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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Julien Sage

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Open access Sep 2026

Transcriptional networks underlying tumour plasticity in small-cell lung cancer

Across human malignancies, the ability of cancer cells to switch states (“plasticity”) drives progression, metastasis and therapy resistance 1–3. Here we investigated the transcriptional and epigenetic basis of plasticity in small-cell lung cancer (SCLC), an aggressive, treatment-refractory cancer 4, 5. SCLC tumours di...

Debadrita Bhattacharya, S. Groves, Cameron Walker et al. · 0 citations
Review Aug 2026

Biomarker-Driven Insights into Immune Checkpoint Inhibitor Therapy in Small-Cell Lung Cancer.

The pivotal roles of biomarkers in SCLC are highlighted, underscoring their contributions to treatment resistance across tumor-intrinsic mechanisms, immune landscape of the tumor microenvironment (TME) and systemic host factors.

Shu-Xing Wang, Xin-rui Zhao, Yue-Yue Zeng et al. · 0 citations

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