Review
of Vancomycin and Dosing Regimen in Critically Ill Patients With Sepsis or Septic Shock: A Narrative Review
Jullius Ivan Mahadhika, Ika Puspita, Gadjah Mada
· 0 citations
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Review
Open access
Sep 2026
Pharmacokinetics of Vancomycin and Dosing Regimen in Critically Ill Patients With Sepsis or Septic Shock: A Narrative Review
Background: Vancomycin is a drug of choice in Methicillin-resistant Staphylococcus aureus (MRSA) infection. The AUC24/MIC of 400-600 μg·h/mL is recommended to achieve therapeutic outcome and prevent nephrotoxicity. In critically ill patients with sepsis/septic shock, various physiological changes may impact vancomycin...
Jullius Ivan Mahadhika, I. P. Sari, Purwantiningsih Purwantiningsih
· Academic Hospital Journal · 0 citations