Open access
Sep 2026
Photoreceptor outer segments promote the accumulation of lipid droplets in microglia by reprogramming lipid metabolism
Findings reveal a lipid-mediated mechanism that drives microglial phenotypic switching and provide a more physiologically relevant in vivo model to mimic microglial activation in degenerative retinas than LPS stimulation.
Ling-Ling Ge, Dan-Yang Yu, Ling-Yan Yan et al.
· Frontiers in Immunology · 0 citations