Author

Jun Dai

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Review Oct 2026

RNA-Dependent RNA Polymerase (RdRp): Structure, Function, and Antiviral Targeting in RNA Viruses.

RNA-dependent RNA polymerase (RdRp) is the core catalytic enzyme that mediates RNA viral replication and transcription. The polymerase facilitates template and substrate channel assembly, nucleotide selectivity, and phosphodiester bond formation, making it an essential component of the viral life cycle. RdRps differ gr...

Wei Liu, Yi-Yi Feng, Fan-Xin Liu et al. · Antiviral Research · 0 citations

Open access Aug 2026

The K247 ubiquitination site of the Newcastle disease virus M protein enhances viral budding to facilitate rapid exploitation of host cell sphingolipid metabolites

Using recombinant viruses generated in this study, the effects of the K247 ubiquitination site on host cell metabolism are investigated and indicate that the K247 residue of the NDV M protein enhances viral budding and promotes rapid utilization of host sphingolipids.

Jun Dai, Fan-Xin Liu, Yiyi Feng et al. · Poultry Science · 0 citations