Author

Jun-Fei Shao

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Case report Open access Sep 2026

A case report of delayed-diagnosed adult multisystem Langerhans cell histiocytosis with isolated MAP2K1 somatic mutation and systematic literature review

Numerous case reports regarding adult multisystem Langerhans cell histiocytosis (MS-LCH) have been published, yet the vast majority only describe single-organ involvement. Cases presenting sequential multi-organ lesions, clinical manifestations mimicking idiopathic hypophysitis and refractory gastritis, accompanied by...

Qi-Jian Zhang, Ping He, Yang Dong et al. · Frontiers in Oncology · 0 citations

Open access Aug 2026

The gut-immune-brain axis in CNS tumors: Causal roles of microbiota and inflammatory proteins unveiled by Mendelian randomization and single-cell transcriptomics

There is a growing number of research suggesting that there is an association between gut microbiota and central nervous system (CNS) tumor. However, the causal relationships and the mediation effects of inflammatory proteins in the associations are unclear. We extracted genetic variants associated with gut microbiota,...

Xian-Wen Cao, Hui Guo, Kun Wang et al. · Medicine · 0 citations