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Author

Jun-Feng Hou

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Review Open access Sep 2026

Multidimensional Roles of the Transcription Factor EB-Regulated Autophagy-Lysosomal Network in Tumor Drug Resistance.

Chemotherapy resistance is a key factor in tumor recurrence and mortality and a barrier to durable therapeutic effectiveness. Besides canonical mechanisms, including target alterations and drug efflux, tumor cells integrate chemotherapy-induced DNA damage, oxidative stress, and metabolic stress into persistent adaptive...

Yue-Li Lu, Yue-Wen Wang, Da-Ying Sun et al. · 0 citations
Open access Aug 2026

Integrative Multi-Omics Mendelian Randomization Identifies BLMH as a Keratinocyte-Enriched Protective Candidate Gene and Potential Therapeutic Target in Psoriasis

An integrative multi-omics analysis nominates BLMH as a keratinocyte-enriched protective candidate gene in psoriasis and suggests tamibarotene as a potential repurposed compound for further investigation.

Rui Shen, Bin-Yi Ran, Jia-Zheng Liu et al. · 0 citations

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