Association Between Respiratory Exacerbations and Accelerated Lung Function Decline in Chronic Obstructive Pulmonary Disease: A Prospective Observational Population-based Cohort Study.
BACKGROUND Moderate-to-severe and severe respiratory exacerbations in chronic obstructive pulmonary disease (COPD) accelerate lung function decline. However, whether any mild-to-severe exacerbations are associated with lung function decline in COPD remains unclear, especially in mild-to-moderate COPD and in the Global...