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Author

Jun-Feng Zhou

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2 papers indexed here

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Sep 2026

T-2 toxin-induced neurotoxicity in juvenile rats involves hippocampal oxidative stress-ER stress-mediated neuronal apoptosis and potential gut-brain axis involvement.

T-2 toxin, a common Fusarium-derived mycotoxin, poses severe threats to livestock production and public health and exhibits potent neurotoxicity by disrupting blood-brain barrier integrity and neuronal function. However, the detailed mechanisms responsible for its developmental neurotoxicity remain poorly elucidated. T...

Jun-Feng Zhou, Jia-Yi Ma, Hong-Yu Wang et al. · 0 citations
Open access Sep 2026

SIRT1/PGC-1α-regulated mitochondrial biogenesis is involved in T-2 toxin-induced chondrocyte injury.

T-2 toxin, a type A trichothecene mycotoxin, has been implicated as an environmental risk factor for Kashin-Beck disease (KBD), an endemic osteoarthropathy characterized by cartilage damage. However, whether T-2 toxin impairs mitochondrial biogenesis in chondrocytes and the underlying regulatory mechanism remain unclea...

Chenxi Wang, Jun-Feng Zhou, Wei-Chang Zhang et al. · 0 citations

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