Open access
Oct 2026
Tie1 ectodomain cleavage governs vascular responses to inflammatory stimulation but is dispensable for angiogenic signaling
Ectodomain cleavage of the vascular receptor Tie1 distinguishes the inflammatory from the angiogenic functions of Angiopoietin-Tie signaling, mechanistically uncoupling two fundamental vascular programs.
Miki Kamiyama, Jing-Jing Shi, L. Rinck et al.
· Journal of Clinical Investig... · 0 citations