Jun-Hong Ling

Inflammation-responsive sodium alginate-based microalgal hydrogel with pH/ROS dual sensitivity for oral colon-targeted therapy of ulcerative colitis.

Ulcerative colitis (UC) is associated with epithelial barrier disruption, oxidative stress, inflammation, and gut microbiota dysbiosis. Oral colon-localized delivery remains challenging because therapeutic cargos must resist gastric exposure, avoid premature release, be retained at inflamed colonic sites, and respond t...