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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Jun-Hu Yuan

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Open access Aug 2026

KRAS and SKIL mutations synergistically promote pancreatic tumorigenesis through the ubiquitin-proteasome-mediated degradation of Smad4

A novel synergy between SKIL loss and KRAS activation that drives pancreatic tumorigenesis through targeted Smad4 degradation is identified and aids in identifying high-risk populations for pancreatic cancer, specifically those harboring KRAS mutations.

Chen-Xi Wang, Ya-Rui Ma, Haixia Cheng et al. · 0 citations

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